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Rat Htra2 cDNA Clone(NM_001106599.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006354

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Gene Information

Cat. No. CDFR006354
Description NativeORF clone of Rattus norvegicus HtrA serine peptidase 2 (Htra2), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001106599.2
Product Type cDAN Clone
Gene Abbr Htra2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene HTRA2
Background This gene encodes a serine protease. The protein has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen-activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat-containing 4. Nuclear localization of this protein has also been observed. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
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