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Rat Hspb1 ORF Clone(NM_031970.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR379990

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Gene Information

Cat. No. CDCR379990
Product Type ORF Clone
Gene Abbr Hspb1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 618 bp
Vector pCMV6-Entry
Target Gene HSPB1
Background This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. [provided by RefSeq, Aug 2017]
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