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Rat Hsd17b4 cDNA Clone(NM_024392.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012335

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Gene Information

Cat. No. CDFR012335
Description NativeORF clone of Rattus norvegicus hydroxysteroid (17-beta) dehydrogenase 4 (Hsd17b4) as transfection-ready DNA NM_024392.2
Product Type cDAN Clone
Gene Abbr Hsd17b4
Species Rat
Vector pCMV6Entry
Target Gene HSD17B4
Background The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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