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Rat Hscb cDNA Clone(NM_001108340.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007976

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Gene Information

Cat. No. CDFR007976
Description NativeORF clone of Rattus norvegicus HscB iron-sulfur cluster co-chaperone homolog (E. coli) (Hscb) as transfection-ready DNA NM_001108340.1
Product Type cDAN Clone
Gene Abbr Hscb
Species Rat
Vector pCMV6Entry
Target Gene HSCB
Background This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
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