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Rat Homer3 cDNA Clone(NM_053310.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013067

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Gene Information

Cat. No. CDFR013067
Description NativeORF clone of Rattus norvegicus homer homolog 3 (Drosophila) (Homer3) as transfection-ready DNA NM_053310.1
Product Type cDAN Clone
Gene Abbr Homer3
Species Rat
Vector pCMV6Entry
Target Gene HOMER3
Background This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
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