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Rat Hnrnph3 cDNA Clone(NM_001108532.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR008144

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Gene Information

Cat. No. CDFR008144
Description NativeORF clone of Rattus norvegicus heterogeneous nuclear ribonucleoprotein H3 (2H9) (Hnrnph3) as transfection-ready DNA NM_001108532.1
Product Type cDAN Clone
Gene Abbr Hnrnph3
Species Rat
Vector pCMV6Entry
Target Gene HNRNPH3
Background This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008]
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