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Rat Hnrnph2 cDNA Clone(NM_001014019.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003155

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Gene Information

Cat. No. CDFR003155
Description NativeORF clone of Rattus norvegicus heterogeneous nuclear ribonucleoprotein H2 (H) (Hnrnph2) as transfection-ready DNA NM_001014019.1
Product Type cDAN Clone
Gene Abbr Hnrnph2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene HNRNPH2
Background This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that binds to RNAs. It is very similar to the family member HNRPH1. This gene is thought to be involved in Fabray disease and X-linked agammaglobulinemia phenotype. Alternative splicing results in multiple transcript variants encoding the same protein. Read-through transcription between this locus and the ribosomal protein L36a gene has been observed. [provided by RefSeq, Jan 2011]
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