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Rat Hmgb2 cDNA Clone(NM_017187.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011239

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Gene Information

Cat. No. CDFR011239
Description NativeORF clone of Rattus norvegicus high mobility group box 2 (Hmgb2) as transfection-ready DNA NM_017187.2
Product Type cDAN Clone
Gene Abbr Hmgb2
Species Rat
Vector pCMV6Entry
Target Gene HMGB2
Background This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq, Jul 2008]
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