Rat Hif1a cDNA Clone(NM_024359.1)

Name: Rat Hif1a cDNA Clone(NM_024359.1)
SKU: CDFR012304
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR012304

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Product Information

Gene Information

Cat. No.	CDFR012304
Description	NativeORF clone of Rattus norvegicus hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (Hif1a) as transfection-ready DNA NM_024359.1
Product Type	cDAN Clone
Gene Abbr	Hif1a
Species	Rat
Vector	pCMV6Entry

Target Gene

HIF1A

Background

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]

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