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Rat Herc4 ORF Clone(NM_001012074.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR369588

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Gene Information

Cat. No. CDCR369588
Product Type ORF Clone
Gene Abbr Herc4
Species Rat
Tag C-terminal Myc-DDK
ORF Size 3174 bp
Vector pCMV6-Entry
Target Gene HERC4
Background HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]
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