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Rat Hbg1 cDNA Clone(NM_172093.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014734

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Gene Information

Cat. No. CDFR014734
Description NativeORF clone of Rattus norvegicus hemoglobin, gamma A (Hbg1) as transfection-ready DNA NM_172093.1
Product Type cDAN Clone
Gene Abbr Hbg1
Species Rat
Vector pCMV6Entry
Target Gene HBG1
Background The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
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