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Rat Hbb cDNA Clone(NM_033234.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013008

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Gene Information

Cat. No. CDFR013008
Description NativeORF clone of Rattus norvegicus hemoglobin beta chain complex (Hbb) as transfection-ready DNA NM_033234.1
Product Type cDAN Clone
Gene Abbr Hbb
Species Rat
Vector pCMV6Entry
Target Gene HBB
Background The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]
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