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Rat Gucy2d cDNA Clone(NM_130737.4)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013910

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Gene Information

Cat. No. CDFR013910
Description NativeORF clone of Rattus norvegicus guanylate cyclase 2d (Gucy2d) as transfection-ready DNA NM_130737.4
Product Type cDAN Clone
Gene Abbr Gucy2d
Species Rat
Vector pCMV6Entry
Target Gene GUCY2D
Background This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq, Dec 2008]
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