Transfected Stable Cell Lines
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Cat. No. : CDCR376343
| Cat. No. | CDCR376343 |
| Product Type | ORF Clone |
| Gene Abbr | Gria4 |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 1302 bp |
| Vector | pCMV6-Entry |
| Target Gene | GRIA4 |
| Background | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008] |
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