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Rat Gpt ORF Clone(NM_031039.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR379537

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Product Information

Gene Information

Cat. No. CDCR379537
Product Type ORF Clone
Gene Abbr Gpt
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1491 bp
Vector pCMV6-Entry
Target Gene GPT
Background This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
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