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Rat Gphn cDNA Clone(NM_022865.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012139

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Gene Information

Cat. No. CDFR012139
Description NativeORF clone of Rattus norvegicus gephyrin (Gphn) as transfection-ready DNA NM_022865.3
Product Type cDAN Clone
Gene Abbr Gphn
Species Rat
Vector pCMV6Entry
Target Gene GPHN
Background This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008]
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