Rat Gper cDNA Clone(NM_133573.1)

Name: Rat Gper cDNA Clone(NM_133573.1)
SKU: CDFR014090
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014090

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Product Information

Gene Information

Cat. No.	CDFR014090
Description	NativeORF clone of Rattus norvegicus G protein-coupled estrogen receptor 1 (Gper) as transfection-ready DNA NM_133573.1
Product Type	cDAN Clone
Gene Abbr	Gper
Species	Rat
Vector	pCMV6Entry

Target Gene

GPER

Background

This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function. [provided by RefSeq, Aug 2017]

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