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Rat Gmnn ORF Clone(NM_001106112.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR372883

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Product Information

Gene Information

Cat. No. CDCR372883
Product Type ORF Clone
Gene Abbr Gmnn
Species Rat
Tag C-terminal Myc-DDK
ORF Size 621 bp
Vector pCMV6-Entry
Target Gene GMNN
Background This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]
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