Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR014757
| Cat. No. | CDFR014757 |
| Description | NativeORF clone of Rattus norvegicus GM2 ganglioside activator (Gm2a) as transfection-ready DNA NM_172335.2 |
| Product Type | cDAN Clone |
| Gene Abbr | Gm2a |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | GM2A |
| Background | This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009] |
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