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Rat Gm2a cDNA Clone(NM_172335.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014757

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Gene Information

Cat. No. CDFR014757
Description NativeORF clone of Rattus norvegicus GM2 ganglioside activator (Gm2a) as transfection-ready DNA NM_172335.2
Product Type cDAN Clone
Gene Abbr Gm2a
Species Rat
Vector pCMV6Entry
Target Gene GM2A
Background This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
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