Rat Gh1 cDNA Clone(NM_001034848.2)

Name: Rat Gh1 cDNA Clone(NM_001034848.2)
SKU: CDFR004395
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR004395

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Product Information

Gene Information

Cat. No.	CDFR004395
Description	NativeORF clone of Rattus norvegicus growth hormone 1 (Gh1) as transfection-ready DNA NM_001034848.2
Product Type	cDAN Clone
Gene Abbr	Gh1
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

GH1

Background

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]

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