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Rat Gemin2 cDNA Clone(NM_053389.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013136

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Gene Information

Cat. No. CDFR013136
Description NativeORF clone of Rattus norvegicus survival of motor neuron protein interacting protein 1 (Sip1) as transfection-ready DNA NM_053389.1
Product Type cDAN Clone
Gene Abbr Gemin2
Species Rat
Vector pCMV6Entry
Target Gene GEMIN2
Background This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. [provided by RefSeq, Aug 2011]
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