Rat Gdf1 cDNA Clone(NM_001044240.2)

Name: Rat Gdf1 cDNA Clone(NM_001044240.2)
SKU: CDFR004765
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR004765

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Product Information

Gene Information

Cat. No.	CDFR004765
Description	NativeORF clone of Rattus norvegicus growth differentiation factor 1 (Gdf1) as transfection-ready DNA NM_001044240.2
Product Type	cDAN Clone
Gene Abbr	Gdf1
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

GDF1

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. The encoded protein is translated from a bicistronic mRNA that also encodes ceramide synthase 1. Mutations in this gene are associated with several congenital cardiovascular malformations. [provided by RefSeq, Jul 2016]

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