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Rat Gcg ORF Clone(NM_012707.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR377568

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Product Information

Gene Information

Cat. No. CDCR377568
Product Type ORF Clone
Gene Abbr Gcg
Species Rat
Tag C-terminal Myc-DDK
ORF Size 543 bp
Vector pCMV6-Entry
Target Gene GCG
Background The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
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