Rat Gar1 cDNA Clone(NM_001024306.1)

Name: Rat Gar1 cDNA Clone(NM_001024306.1)
SKU: CDFR003580
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR003580

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Product Information

Gene Information

Cat. No.	CDFR003580
Description	NativeORF clone of Rattus norvegicus nucleolar protein family A, member 1 (H/ACA small nucleolar RNPs) (Nola1) as transfection-ready DNA NM_001024306.1
Product Type	cDAN Clone
Gene Abbr	Gar1
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

GAR1

Background

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene. [provided by RefSeq, Jul 2008]

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