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Rat Galnt1 cDNA Clone(NM_024373.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012317

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Gene Information

Cat. No. CDFR012317
Description NativeORF clone of Rattus norvegicus UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) as transfection-ready DNA NM_024373.1
Product Type cDAN Clone
Gene Abbr Galnt1
Species Rat
Vector pCMV6Entry
Target Gene GALNT1
Background This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature. [provided by RefSeq, Jul 2008]
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