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Rat Gabrd ORF Clone(NM_017289.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR378391

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Product Information

Gene Information

Cat. No. CDCR378391
Product Type ORF Clone
Gene Abbr Gabrd
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1350 bp
Vector pCMV6-Entry
Target Gene GABRD
Background Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
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