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Rat Gab2 cDNA Clone(NM_053417.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013161

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Gene Information

Cat. No. CDFR013161
Description NativeORF clone of Rattus norvegicus GRB2-associated binding protein 2 (Gab2) as transfection-ready DNA NM_053417.1
Product Type cDAN Clone
Gene Abbr Gab2
Species Rat
Vector pCMV6Entry
Target Gene GAB2
Background This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009]
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