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Rat G6pd ORF Clone(NM_017006.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR378119

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Gene Information

Cat. No. CDCR378119
Product Type ORF Clone
Gene Abbr G6pd
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1548 bp
Vector pCMV6-Entry
Target Gene G6PD
Background This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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