Transfected Stable Cell Lines
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Cat. No. : CDCR373648
| Cat. No. | CDCR373648 |
| Product Type | ORF Clone |
| Gene Abbr | Fyco1 |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 4356 bp |
| Vector | pCMV6-Entry |
| Target Gene | FYCO1 |
| Background | The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2). [provided by RefSeq, Aug 2020] |
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