Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR006479
| Cat. No. | CDFR006479 |
| Description | NativeORF clone of Rattus norvegicus fibronectin leucine rich transmembrane protein 2 (Flrt2) as transfection-ready DNA NM_001106750.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Flrt2 |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | FLRT2 |
| Background | This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] |
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