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Rat Flrt2 cDNA Clone(NM_001106750.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006479

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Gene Information

Cat. No. CDFR006479
Description NativeORF clone of Rattus norvegicus fibronectin leucine rich transmembrane protein 2 (Flrt2) as transfection-ready DNA NM_001106750.1
Product Type cDAN Clone
Gene Abbr Flrt2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene FLRT2
Background This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
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