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Rat Fga ORF Clone(NM_001008724.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR368950

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Gene Information

Cat. No. CDCR368950
Product Type ORF Clone
Gene Abbr Fga
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2349 bp
Vector pCMV6-Entry
Target Gene FGA
Background This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. [provided by RefSeq, Jan 2016]
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