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Rat Fermt3 cDNA Clone(NM_001127543.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009569

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Gene Information

Cat. No. CDFR009569
Description NativeORF clone of Rattus norvegicus fermitin family homolog 3 (Drosophila) (Fermt3) as transfection-ready DNA NM_001127543.1
Product Type cDAN Clone
Gene Abbr Fermt3
Species Rat
Vector pCMV6Entry
Target Gene FERMT3
Background Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010]
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