Rat Fbxw2 cDNA Clone(NM_001107835.2)

Name: Rat Fbxw2 cDNA Clone(NM_001107835.2)
SKU: CDFR007487
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR007487

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Product Information

Gene Information

Cat. No.	CDFR007487
Description	NativeORF clone of Rattus norvegicus F-box and WD repeat domain containing 2 (Fbxw2) as transfection-ready DNA NM_001107835.2
Product Type	cDAN Clone
Gene Abbr	Fbxw2
Species	Rat
Vector	pCMV6Entry

Target Gene

FBXW2

Background

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008]

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