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Rat Fbxl8 cDNA Clone(NM_001109128.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR008674

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Gene Information

Cat. No. CDFR008674
Description NativeORF clone of Rattus norvegicus F-box and leucine-rich repeat protein 8 (Fbxl8) as transfection-ready DNA NM_001109128.1
Product Type cDAN Clone
Gene Abbr Fbxl8
Species Rat
Vector pCMV6Entry
Target Gene FBXL8
Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78% sequence identity with the mouse protein. [provided by RefSeq, Jul 2008]
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