Rat Fanca cDNA Clone(NM_001108455.1)

Name: Rat Fanca cDNA Clone(NM_001108455.1)
SKU: CDFR008069
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR008069

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Product Information

Gene Information

Cat. No.	CDFR008069
Description	NativeORF clone of Rattus norvegicus Fanconi anemia, complementation group A (Fanca) as transfection-ready DNA NM_001108455.1
Product Type	cDAN Clone
Gene Abbr	Fanca
Species	Rat
Vector	pCMV6Entry

Target Gene

FANCA

Background

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008]

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