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Rat Erlin2 cDNA Clone(NM_001106088.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005669

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Gene Information

Cat. No. CDFR005669
Description NativeORF clone of Rattus norvegicus ER lipid raft associated 2 (Erlin2) as transfection-ready DNA NM_001106088.2
Product Type cDAN Clone
Gene Abbr Erlin2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ERLIN2
Background This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
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