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Rat Epsti1 cDNA Clone(NM_001044257.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004778

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Gene Information

Cat. No. CDFR004778
Description NativeORF clone of Rattus norvegicus epithelial stromal interaction 1 (breast) (Epsti1) as transfection-ready DNA NM_001044257.1
Product Type cDAN Clone
Gene Abbr Epsti1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene EPSTI1
Background The protein encoded by this gene has been shown to promote tumor invasion and metastasis in some invasive cancer cells when overexpressed. Expression of this gene has been shown to be upregulated by direct binding of the Kruppel like factor 8 protein to promoter sequences. The translated protein interacts with the amino terminal region of the valosin containing protein gene product, resulting in the nuclear translocation of the nuclear factor kappa B subunit 1 gene product, and activation of target genes. Overexpression of this gene has been observed in some breast cancers and in some individuals with systemic lupus erythematosus (SLE). [provided by RefSeq, Sep 2016]
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