Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR014748
| Cat. No. | CDFR014748 |
| Description | NativeORF clone of Rattus norvegicus elaC homolog 2 (E. coli) (Elac2) as transfection-ready DNA NM_172326.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Elac2 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | ELAC2 |
| Background | The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
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