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Rat Elac2 cDNA Clone(NM_172326.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014748

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Gene Information

Cat. No. CDFR014748
Description NativeORF clone of Rattus norvegicus elaC homolog 2 (E. coli) (Elac2) as transfection-ready DNA NM_172326.1
Product Type cDAN Clone
Gene Abbr Elac2
Species Rat
Vector pCMV6Entry
Target Gene ELAC2
Background The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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