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Rat Eif6 cDNA Clone(NM_001037352.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004523

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Gene Information

Cat. No. CDFR004523
Description NativeORF clone of Rattus norvegicus eukaryotic translation initiation factor 6 (Eif6) as transfection-ready DNA NM_001037352.1
Product Type cDAN Clone
Gene Abbr Eif6
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene EIF6
Background Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]
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