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Rat Eif2ak2 cDNA Clone(NM_019335.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011422

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Gene Information

Cat. No. CDFR011422
Description NativeORF clone of Rattus norvegicus eukaryotic translation initiation factor 2-alpha kinase 2 (Eif2ak2) as transfection-ready DNA NM_019335.1
Product Type cDAN Clone
Gene Abbr Eif2ak2
Species Rat
Vector pCMV6Entry
Target Gene EIF2AK2
Background The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021]
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