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Rat Ei24 cDNA Clone(NM_001025660.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004017

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Gene Information

Cat. No. CDFR004017
Description NativeORF clone of Rattus norvegicus etoposide induced 2.4 mRNA (Ei24) as transfection-ready DNA NM_001025660.1
Product Type cDAN Clone
Gene Abbr Ei24
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene EI24
Background This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014]
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