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Rat Edn1 cDNA Clone(NM_012548.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010368

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Gene Information

Cat. No. CDFR010368
Description NativeORF clone of Rattus norvegicus endothelin 1 (Edn1) as transfection-ready DNA NM_012548.2
Product Type cDAN Clone
Gene Abbr Edn1
Species Rat
Vector pCMV6Entry
Target Gene EDN1
Background This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
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