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Rat Eddm3b cDNA Clone(NM_178103.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014919

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Gene Information

Cat. No. CDFR014919
Description NativeORF clone of Rattus norvegicus family with sequence similarity 12, member B (epididymal) (Fam12b) as transfection-ready DNA NM_178103.2
Product Type cDAN Clone
Gene Abbr Eddm3b
Species Rat
Vector pCMV6Entry
Target Gene EDDM3B
Background Testicular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq, Jul 2008]
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