Rat Dusp5 cDNA Clone(NM_133578.1)

Name: Rat Dusp5 cDNA Clone(NM_133578.1)
SKU: CDFR014094
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014094

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Product Information

Gene Information

Cat. No.	CDFR014094
Description	NativeORF clone of Rattus norvegicus dual specificity phosphatase 5 (Dusp5) as transfection-ready DNA NM_133578.1
Product Type	cDAN Clone
Gene Abbr	Dusp5
Species	Rat
Vector	pCMV6Entry

Target Gene

DUSP5

Background

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus. [provided by RefSeq, Jul 2008]

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