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Rat Dusp18 cDNA Clone(NM_001013128.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002853

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Gene Information

Cat. No. CDFR002853
Description NativeORF clone of Rattus norvegicus dual specificity phosphatase 18 (Dusp18) as transfection-ready DNA NM_001013128.1
Product Type cDAN Clone
Gene Abbr Dusp18
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene DUSP18
Background Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]
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