Rat Dusp11 cDNA Clone(NM_001025650.1)

Name: Rat Dusp11 cDNA Clone(NM_001025650.1)
SKU: CDFR004007
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR004007

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Product Information

Gene Information

Cat. No.	CDFR004007
Description	NativeORF clone of Rattus norvegicus dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) (Dusp11) as transfection-ready DNA NM_001025650.1
Product Type	cDAN Clone
Gene Abbr	Dusp11
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

DUSP11

Background

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. [provided by RefSeq, Sep 2008]

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