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Rat Dnm2 cDNA Clone(NM_013199.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010984

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Gene Information

Cat. No. CDFR010984
Description NativeORF clone of Rattus norvegicus dynamin 2 (Dnm2) as transfection-ready DNA NM_013199.1
Product Type cDAN Clone
Gene Abbr Dnm2
Species Rat
Vector pCMV6Entry
Target Gene DNM2
Background Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
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