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Rat Dnase2b cDNA Clone(NM_021664.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011717

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Gene Information

Cat. No. CDFR011717
Description NativeORF clone of Rattus norvegicus deoxyribonuclease II beta (Dnase2b) as transfection-ready DNA NM_021664.1
Product Type cDAN Clone
Gene Abbr Dnase2b
Species Rat
Vector pCMV6Entry
Target Gene DNASE2B
Background The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
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