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Rat Dnaja1 cDNA Clone(NM_022934.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012157

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Gene Information

Cat. No. CDFR012157
Description NativeORF clone of Rattus norvegicus DnaJ (Hsp40) homolog, subfamily A, member 1 (Dnaja1) as transfection-ready DNA NM_022934.1
Product Type cDAN Clone
Gene Abbr Dnaja1
Species Rat
Vector pCMV6Entry
Target Gene DNAJA1
Background This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes. [provided by RefSeq, Sep 2015]
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