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Rat Dnai1 cDNA Clone(NM_001024342.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003614

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Gene Information

Cat. No. CDFR003614
Description NativeORF clone of Rattus norvegicus dynein, axonemal, intermediate chain 1 (Dnai1) as transfection-ready DNA NM_001024342.1
Product Type cDAN Clone
Gene Abbr Dnai1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene DNAI1
Background This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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